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NFL Week 11 Inactives: Key Injuries to Watch and Who to Start or Sit

Week 11 of the NFL season is shaping up to be a critical one for fantasy football managers, with several key players ruled out or listed as questionable ahead of Sunday’s action.

As always, keeping an eye on the inactives list is crucial to setting your lineup correctly and avoiding any surprises. Below, we break down the notable inactives and injury updates to help you make the best decisions for your fantasy team.

Early Sunday Inactives

Sam LaPorta, TE, Detroit Lions – Shin (OUT)
LaPorta has been a breakout star for the Lions this season, but a shin injury will sideline him in Week 11. In his absence, Brock Wright will step in as Detroit’s starting tight end. For fantasy managers, LaPorta’s absence is a significant blow, and it’s advisable to look for other streaming options on the waiver wire, particularly if you’re relying on him as a TE1.

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MarShawn Lloyd, RB, Green Bay Packers – Illness (OUT)
Lloyd was already dealing with injury concerns earlier in the season, including ankle and hamstring issues. Now, he’s facing an illness that could potentially end his season, making it difficult for him to make a return this year. The Packers’ backfield will continue to lean heavily on Aaron Jones and A.J. Dillon for the foreseeable future.

Trevor Lawrence, QB, Jacksonville Jaguars – Shoulder (OUT)
The Jaguars will be without their starting quarterback this week as Trevor Lawrence nurses a shoulder injury. Backup Mac Jones will start under center for Jacksonville, although fantasy managers should consider this a downgrade for the Jaguars’ offensive weapons. Lawrence is targeting a return in Week 13 after the team’s bye, so this will be a tough blow for those relying on him in fantasy.

Tank Bigsby, RB, Jacksonville Jaguars – Ankle (OUT)
Bigsby’s absence means Travis Etienne Jr. will see the majority of carries in the Jaguars’ backfield. Etienne should remain a strong RB1 option for fantasy managers, with D’Ernest Johnson stepping into the backup role. Bigsby’s injury only solidifies Etienne’s workhorse role going forward.

Harrison Bryant, TE, Las Vegas Raiders – Ankle (OUT)
Bryant was a backup to Brock Bowers in the Raiders’ tight end room, but his ankle injury will keep him out this week. For those in deeper leagues, it’s worth monitoring how the tight end situation unfolds in Vegas, but Michael Mayer will likely continue to see the bulk of the work.

Jamaal Williams, RB, New Orleans Saints – Groin (OUT)
With Jamaal Williams sidelined, Taysom Hill will continue to serve as the Saints’ primary backup running back behind Alvin Kamara. Hill’s multi-position eligibility makes him an intriguing fantasy play, and he should remain a top option for those looking for running back depth or a high-risk, high-reward flex play.

Cedrick Wilson Jr., WR, New Orleans Saints – Shoulder (Questionable)
Wilson’s questionable status could impact the Saints’ receiving corps, especially if he doesn’t suit up. If Wilson is inactive, Marquez Valdes-Scantling may see a slight uptick in fantasy value as a potential flex play. However, with the Saints’ offense focused on Kamara and Hill, Wilson’s absence may not dramatically change the fantasy landscape.

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Afternoon Inactives

Dalton Kincaid, TE, Buffalo Bills – Knee (OUT)
Kincaid is out for Week 11, which opens the door for Dawson Knox to get more involved in the offense. Knox should see an increase in targets, but fantasy managers may want to look for better streaming options, as the Bills’ offense has been inconsistent this season, particularly at the tight end position.

Amari Cooper, WR, Buffalo Bills – Wrist (Questionable)
Amari Cooper’s injury is something to monitor closely. All indications point to Cooper playing, but if he is limited, it could affect his ability to produce at his usual high level. If Cooper is not at 100%, expect more targets to go toward other receivers like Stefon Diggs, and Cooper’s fantasy upside will be capped.

Josh Reynolds, WR, Denver Broncos – Hand (OUT/IR)
Reynolds is still recovering from surgery, which leaves Devaughn Vele as the next man up in the Broncos’ receiving corps. Vele has limited fantasy value but could be a deep-league option in PPR formats if you’re desperate for a flyer.

Isiah Pacheco, RB, Kansas City Chiefs – Ankle (OUT/IR)
Pacheco is out for Week 11, which means Kareem Hunt will once again handle the bulk of the backfield duties for the Chiefs. Hunt has been serviceable in Pacheco’s absence and should continue to be a solid RB2 option, particularly in deeper formats.

Harrison Butker, K, Kansas City Chiefs – Knee (OUT/IR)
With Harrison Butker out, Spencer Shrader will take over as the Chiefs’ kicker for Week 11. While kickers are often an afterthought in fantasy football, Butker’s absence may affect Kansas City’s offensive rhythm, particularly in close games.

Noah Fant, TE, Seattle Seahawks – Groin (OUT)
Fant will miss Week 11, which means AJ Barner will start in his place. While Seattle’s passing game isn’t heavily reliant on the tight end, those in deeper leagues may want to consider Barner as a short-term option for a fill-in start.

Sunday Night Game Inactives

Charlie Jones, WR, Cincinnati Bengals – Groin (OUT)
Jones has been a role player in the Bengals’ offense, and with him sidelined, Tee Higgins (who had previously been dealing with a quad issue) has been removed from the injury report. Higgins should be good to go for the Bengals, and his return will be a boost to the Cincinnati passing attack, especially for fantasy managers who have him in their lineups.

Final Thoughts

As fantasy managers finalize their lineups for Week 11, the injury report is filled with some key names who could make or break matchups. With several key players either ruled out or listed as questionable, such as Trevor Lawrence, Isiah Pacheco, and Sam LaPorta, adjustments will need to be made. Keep an eye on the official inactives list as the morning progresses, and be sure to pivot to reliable backups like Travis Etienne Jr., Taysom Hill, and Dawson Knox if needed. Stay on top of these injury updates to maximize your lineup potential and avoid any unwanted surprises on Sunday morning.

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